Blood Platelet Disorders
Blood Platelet Articles

Blood Platelet Disorders: Variety of Chaos

Blood is life.  Without it, there is no way for the body to survive or even function.  When blood platelet disorders occur, the body suffers.  Health is affected and so does the performance of the body's organs.  Disorders in the blood platelets can also lead to serious complications.  The most common types of disorders include:

Adhesion Blood Platelet Disorder

This disorder is also known as the Bernard-Soulier Syndrome.  A deficiency exists on the exterior of Glycoprotein Ib/IX, an area found on the platelet.  In normal blood platelets where this is present, platelets are capable of clumping together.  In this type of blood platelet disorder, they fail to do so.

This disorder leads to easy bruising, bleeding in the mouth and/or gums and even the gastrointestinal tract.  This type of blood platelet disorder can also lead to a condition called menorrhagia in women, which is characterized by heavy menstruations.

Blood Platelet Disorder and Procoagulant Activity

Also referred to as Scott Syndrome, this disorder is characterized by the failure of the blood platelets to activate proteins that cause blood clotting.  This disorder doesn’t always lead to abnormal bleeding or aggregation of the blood platelets but certain abnormalities will often be found on the surface of the platelet membrane.

Blood Platelet Disorder and Functions

Certain disorders are caused by drugs and medications.  These include certain antibiotics, aspirin and aspirin-containing drugs, certain NSAIDs such as ibuprofen, naproxen ticlopidine and indomethacin, anti-coagulants, anti-histamines, anesthetics, anti-depressants and heart drugs.

The type of disorder caused by these drugs is temporary, though.  The normal blood platelet count goes back to normal once the patient stops taking the drugs.

Blood Platelet Immune-mediated Disorders

Certain blood platelet disorders are brought about by problems with the immune system.  In these blood platelet disorders, the blood platelets are destroyed but not the bone marrow's ability to replenish them. 

The most common of these disorders is ITP or immune thrombocytopenic purpura.  In this type of blood platelet disorder, the immune system treats platelets as invaders.  It then sends antibodies to recognize and destroy the blood platelets, usually occurring in a person's spleen. 

Sometimes, this type of blood platelet disorder may be caused by environmental triggers like bacteria and viruses.  In this disorder, the immune system 'thinks' that the foreign bodies look similar to platelet proteins.  Although it might attack the microbes, it can also attack the blood platelets.

Blood Platelet Disorder: Acquired Aplastic Anemia

Another type of blood platelet disorder is actually a group of disorders, characterized by low blood platelet count.  New evidence points that these types of blood platelet disorders may be caused by an immune system gone awry.

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