Blood Platelet Disorders
Blood Platelet Articles

Chronic Lymphocytic Leukemia (CLL)

What is Chronic Lymphocytic Leukemia?

CLL, a cancer affecting the blood, bone marrow, and the lymph system, is the most common form of leukemia found in the adult population of the western hemisphere. The body’s white blood cells (lymphocytes) lose their all-important ability to fight infection. In a healthy body, bone marrow naturally produces stem cells which become an integral part of blood cell formation. These cells are naturally and continually replaced in their life cycle pattern .

The functionality of that cycle is destroyed in this specific monoclonal disorder. The body produces and collects abnormal lymphocytes at too great a rate, crowding out the healthy cells which would normally bolster the immune system.

In the U.S., close to 10, 000 people per year are diagnosed with CLL. Men are two times more likely to develop CLL than women. In 75% of all new cases the patients are over the age of 50. Although recently, there has been an increase in cases diagnosed in patients under 35.

CLL Symptoms:

  • Enlarged lymph nodes
  • Abnormal bruising (late in the disease)
  • Fatigue
  • Excessive perspiration (night sweats)
  • Loss of appetite
  • Unintentional weight loss

Blood disorders that may visually and clinically resemble CLL are:

  • Mantle cell lymphoma
  • Marginal zone lymphoma
  • B-cell prolymphocytic leukemia
  • Lymphoplasmacytic lymphoma

CLL Causes

No direct causes for CLL have been traced and research has not detected any link to radiation.  However, many types of leukemia have been linked to benzene exposure. In addition, research has found that there seems to be a hereditary component involved. Family members of leukemia patients are three times more likely to develop the disease.

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